A REVIEW ON POLYMERS USED IN MUCOADHESIVE DRUG DELIVERY SYSTEM

Authors

  • Muthukumaran M Jawaharlal Nehru Technological University Anantapur, Anantapur, A.P, India–515 002.
  • Chandra Sekhar K B Jawaharlal Nehru Technological University Anantapur, Anantapur, A.P, India–515 002.
  • Dhachinamoorthi D QIS College of Pharmacy, Vengamukkapalem, Ongole, A.P, India–523 272.
  • Sriram N Research Scholar, Acharya Nagarjuna University, Guntur, A.P, India-522 510

Keywords:

Mucoadhesion, Oral Mucosa, Mucoadhesive Polymers.

Abstract

Mucoadhesion can be defined as a state in which two components, of which one is of biological origin are held together for extended periods of time by the help of interfacial forces mucoadhesion is the attachment of the drug along with a suitable carrier to the mucous membrane. Mucoadhesion is a complex phenomenon which involves wetting, adsorption and interpenetration of polymer chains the mucoadhesive polymers can be categorized into two broad categories, materials which undergo matrix formation or hydrogel formation by either a water swellable material or a water soluble material. Mucoadhesive drug delivery systems is one of the most important novel drug delivery systems with its various advantages and it has a lot of potential in formulating dosage forms for various chronic diseases. The current review provides a good insight on mucoadhesive polymers, the phenomenon of mucoadhesion and the factors which have the ability to affect the mucoadhesive properties of a polymer.

Dimensions

Published

2011-06-02

Issue

Vol. 1 No. 2 (2011): 2011 Volume -1 - Issue 2

Section

Articles
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