NEW VISIBLE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF AMOXICILLIN TRIHYDRATE IN BULK DRUG & THEIR FORMULATIONS

Authors

  • Imam pasha S Global college of pharmacy, Moinabad, R.R.Dist, A.P, India - 504501.
  • Taqui Mohammed Global college of pharmacy, Moinabad, R.R.Dist, A.P, India - 504501.
  • Shravan kumar A Global college of pharmacy, Moinabad, R.R.Dist, A.P, India - 504501.
  • Nikhila V Global college of pharmacy, Moinabad, R.R.Dist, A.P, India - 504501.

Keywords:

Amoxicillin trihydrate, Ferric chloride, 1, 10-Phenanthroline, Spectrophotometry.

Abstract

A simple, sensitive and economical spectrophotometric method was developed for the determination of Amoxicillin trihydrate in pharmaceutical formulations. This method is based on the formation of pink colored chromogen complex by the reaction of drug with ferric chloride and 1,10-Phenanthroline, which absorbs maximally at 510 nm. Beer’s law is obeyed at a concentration range of 2-20 mcg/ml for method. This method has been successfully applied for the assay of the drug in pharmaceutical formulations.

Dimensions

Published

2012-04-18

Issue

Vol. 2 No. 2 (2012): 2012 Volume -2 - Issue 2

Section

Articles
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