NEW VISIBLE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF EMTRICITABINE IN BULK DRUGS AND THEIR FORMULATIONS

Authors

  • Imam pasha S Nizam College of Pharmacy, Deshmukhi, Pochampalli (M), Near Ramoji Film City, Nalgonda, A.P, India – 508284.
  • Taqui Mohammed Nizam College of Pharmacy, Deshmukhi, Pochampalli (M), Near Ramoji Film City, Nalgonda, A.P, India – 508284.
  • Nikhila V Nizam College of Pharmacy, Deshmukhi, Pochampalli (M), Near Ramoji Film City, Nalgonda, A.P, India – 508284.
  • Shravankumar A Nizam College of Pharmacy, Deshmukhi, Pochampalli (M), Near Ramoji Film City, Nalgonda, A.P, India – 508284.
  • Tirupathi D Nizam College of Pharmacy, Deshmukhi, Pochampalli (M), Near Ramoji Film City, Nalgonda, A.P, India – 508284.
  • Gopi T Nizam College of Pharmacy, Deshmukhi, Pochampalli (M), Near Ramoji Film City, Nalgonda, A.P, India – 508284.

Keywords:

Emtricitabine, Mordant black-3, Spectrophotometry.

Abstract

A simple, sensitive and economical spectrophotometric method was developed for the determination of Emtricitabine in pharmaceutical formulations. This method is based on the separation of colored chloroform layer by the reaction of drug with mordant black 3 , which absorbs maximally at 543 nm. Beer’s law is obeyed at a concentration range of 5-90 mcg/ml for method. This method has been successfully applied for the assay of the drug in pharmaceutical formulations.

Dimensions

Published

2012-03-12

Issue

Vol. 2 No. 1 (2012): 2012 Volume -2 - Issue 1

Section

Articles
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