FORMULATION AND EVALUATION OF DOMPERIDONE MALEATE BILAYER TABLET

Authors

  • Pratap B Bhalerao Shree Sureshdada Jain Institute of Pharmaceutical Education & Research, Jamner, Jalgaon, India - 424206.
  • Raundal M J Shree Sureshdada Jain Institute of Pharmaceutical Education & Research, Jamner, Jalgaon, India - 424206.
  • Kandharkar S U Shree Sureshdada Jain Institute of Pharmaceutical Education & Research, Jamner, Jalgaon, India - 424206.
  • Patil P P Shree Sureshdada Jain Institute of Pharmaceutical Education & Research, Jamner, Jalgaon, India - 424206.
  • Bari M M Shree Sureshdada Jain Institute of Pharmaceutical Education & Research, Jamner, Jalgaon, India - 424206.
  • Barhate S D Shree Sureshdada Jain Institute of Pharmaceutical Education & Research, Jamner, Jalgaon, India - 424206.

Keywords:

Bilayer tablet, Domperidone maleate, Sustained release tablet.

Abstract

Bilayer tablet of domperidone maleate formulated and evaluated with same drug in both layer immediate and sustained release biphasic dosage form. Domperidone maleate bilayer tablet prepared using the polymers like HPMC K100M, Metolose as a matrix forming agent and superdisintegrant like Croscarmellose sodium, sodium starch glycolate. Different effect of these polymer concentration and superdisintegrant were studied and evaluated by the dissolution study of prepared bilayer tablet along with weight variation, hardness, friability and content uniformity.

Dimensions

Published

2013-07-03

Issue

Vol. 3 No. 3 (2013): 2013 Volume -3 - Issue 3

Section

Articles
Copyright & Licensing
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