Preparation and evaluation microspheres with HPMC polymer

Authors

Ch.Kishore
editorijipsr@gmail.com
Department of Pharmaceutics, Holy Mary Institute of Technology and Science (College of Pharmacy) Bogaram, Keesara, Ranga Reddy (DT), Telangana State
N.Sriram Department of Pharmaceutics, Holy Mary Institute of Technology and Science (College of Pharmacy) Bogaram, Keesara, Ranga Reddy (DT), Telangana State

Floating microspheres, Ranitidine, In vitro relea-se, Bioavailability

The aim of this study was to formulate and evaluate microspheres of Ranitidine. These formulations are mainly

usefull in inhibition of gastric acid secretion. It shows action on histamine stimulation and gastrin stimulated acid

secretion. The compatability was first checked with FTIR spectrophotometric for drug and excipients. The prepared

product was subjected to various studies like drug entrapment efficiency particle size, bulk density, % yield, %

buoyancy, etc. The individual peaks of each drug and the excipients were compared and the compatibility was

studied and this was done for all the formulations in the preparations.

Dimensions