Formulation and quality evaluations of tulsi tea tablets - a tea diversification product

Authors

  • Prakash Katakam SSS Indira College of Pharmacy, Vishnupuri, Nanded- 431606
  • Koushik Bhandari School of Medical Science and Technology, IIT Kharagpur, 721302
  • Baishakhi De SSS Indira College of Pharmacy, Vishnupuri, Nanded- 431606 School of Medical Science and Technology, IIT Kharagpur, 721302
  • Shanta K Adiki Nirmala College of Pharmacy, Guntur, Andhra Pradesh, 522503
  • Gargi Saha Research Officer, National Tea Research Foundation, Tea Board of India, Kolkata 700001

Keywords:

Tulsi tea extract, Active ingredient, Wet granulation, Micromeritic properties, Post compressional evaluations, Direct compression, Zero order release kinetics, Erosion mechanism

Abstract

This article reports the formulation and quality evaluations of tulsi tea tablets prepared for better applicability. Tulsi

tea extracts (TTE) were prepared by mixing black tea: tulsi in the w/w ratios of 70:30 and tablets were formulated by

a combination of wet granulation and direct compression. Micromeritic properties of the powder blend of TTE and

excipient was carried out prior to tablets compression followed by post compressional evaluations. TTE and excipient

mixed powder blend exhibited excellent flow properties. Post compressional evaluations showed that the formulated

tablets are compliant with the pharmacoepial specifications. Batch F3 formulation is considered to be the optimized

batch with zero order release kinetics and anomalous flow behavior; TTE release from the formulations is said to

follow erosion mechanism. The formulations were stable enough as evident from the results of stability studies. The

tablets prepared were satisfactory in terms of quality aspects and aided in better applicability of tulsi-tea extract.

Dimensions

Published

2018-07-09