Solid lipid nanoparticles (SLNs). A Comprehensive review

Abstract

Solid lipid nanoparticles (SLNs) have become a highly effective nanocolloidal drug delivery method. This review provides up-to-date information on a number of SLN-related topics, including their morphology, structural characteristics, preparation techniques, and characterizations. The potential for surface modification, improved penetration across different biological barriers, resistance to chemical degradation, and the capacity to encapsulate two or more therapeutic compounds at once have all drawn interest to SLNs.  This study highlights current research developments related to this carrier system at the same time. Solid lipid nanoparticles (SLNs), a novel technique of medication delivery, are better soluble and bioavailable. Solid lipid nanoparticles, or SLNs, are at the forefront of the quickly expanding field of nanotechnology and have a number of potential uses in research and medicine delivery. Solid lipid nanoparticles (SLN) consist of a monolayer phospholipid shell surrounding a solid lipid core. Lipid nanoparticles present a chance to create novel treatments because of their special size-dependent characteristics. Drug targeting may be made possible by the novel drug delivery concept made possible by the capacity to put medications into nanocarriers. The development of lipid nanoparticles, their preparation process, subsequent production processes, characterisation, applications, and future were the main topics of this review. This review discusses the benefits and drawbacks of solid lipid nanoparticles in a comprehensive manner.