Role of micronutrients in the management of dengue fever

Abstract

Dengue virus infection is the most widespread mosquito-borne viral infection in humans and has emerged as a serious global health
challenge. In the absence of effective treatment and vaccine, host factors including nutritional status, which may alter disease
progression, need investigation. The interplay between nutrition and other infections is well-established, and modulation of
nutritional status often presents a simple low-cost method of interrupting transmission, reducing susceptibility, and/or ameliorating
disease severity. This review examines the evidence on the role of micronutrients in dengue virus infection. We found critical issues
and often inconsistent results across studies; this finding along with the lack of sufficient literature in this field have limited our
ability to make any recommendations. However, vitamins D and E have shown promise in small supplementation trials. In summary,
the role of micronutrients in dengue virus infection is an exciting research area and needs to be examined in well-designed studies
with larger samples. Dengue is life threatening. It is critical to triage patients with dengue infection in the early stage. However,
there is limited knowledge on early indicators of Severe dengue. The objective of this study is to identify risk factors for the
prognosis of Severe dengue and try to find out some potential predictive factors for Severe dengue from dengue fever in the early
of infection.