THE EMERGING ERA OF GENETICALLY ENGINEERED OFFSPRING

Authors

  • Sk. Shehanaz Assistant Professor, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada
  • Sd. Mubarak Fathima Department of Pharmacy Practice, Vijaya Institute of Pharmaceutical Sciences for Women, Vijayawada, Andhra Pradesh -521108, India.
  • Ch. Kiranmai Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for Women, Vijayawada, Andhra Pradesh -521108, India.
  • S. Sundar Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for Women, Vijayawada, Andhra Pradesh -521108, India.

Keywords:

CCR5, CRISPR-cas9, Gene‐editing, Germ‐line.

Abstract

Genetically engineered offspring are produced by genetic modification to affect the characteristics of the offspring, or from an embryo chosen by pre-implantation genetic diagnosis (PGD). The main goal of designing offspring is to prevent genetically-based disorders that are caused by mutations in DNA. It is now possible to produce precisely modified designer babies—as evidenced by the advancements in mitochondrial DNA transfer and genome editing techniques. But there isn't enough information available about the risks associated with these editing tools, particularly when the changes are inherited. In addition, there are moral questions about whether or not we should use these technologies to produce designer offspring. that further study is needed to refine the technique and determine its long-term safety, and that these germ line genetic editing techniques should still be regarded as experimental operations. created and put into use a teaching module for both an advanced genetics course and a genetics course that introduces students to CRISPR-cas9 technology. The design, strategy, conceptual modelling, and implementation of CRISPR-cas9 technology are based on the current study findings about CCR5 gene editing in twin girls.

Dimensions

Published

2026-03-06