Formulation and Evaluation of Sunscreen Nanoemulsion on Sunflower Oil (Helianthus annus)

Nivetha.M; Karthick .M; Divyaparvathi .R; Manivannan .R; Bagathsingh .C; Deivasundari .P; Nagarajan .V; Srinivas .P; Surendharan .P

Authors

Nivetha.M
editorijpir@gmail.com
Assistant Professor, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Karthick .M Assistant Professor, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Divyaparvathi .R Assistant Professor, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Manivannan .R Professor & Principal, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Bagathsingh .C B.Pharm Final Year Student, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Deivasundari .P B.Pharm Final Year Student, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Nagarajan .V B.Pharm Final Year Student, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Srinivas .P B.Pharm Final Year Student, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.
Surendharan .P B.Pharm Final Year Student, Department of Pharmaceutics, Excel College of Pharmacy, Komarapalayam, Namakkal -637303, Tamilnadu, India.

Keywords:

Sunflower oil, Nanoemulsion, Sunscreen, SPF, Spontaneous emulsification method

Abstract

The study involved the creation of a Nanoemulsion sunscreen using sunflower oil, which contains bioactive compounds with various pharmacological benefits, such as anti-bacterial properties and improved antioxidant effects. The Nanoemulsions were prepared using sunflower oil through a spontaneous emulsification method with three different formulations (F1 (Tween80 8%,sorbitol8.8%), F2 (Tween 80 7.2%, sorbitol8%), F3 (Tween80 6.4%,sorbitol7.2%)).These Nanoemulsions were then evaluated for their physical and chemical properties, solubility, stability, pH, viscosity, percentage drug content, FT-IR and UV analysis, as well as SPF value determination. The results showed that the Nanoemulsion sunscreen remained stable during a 4-week storage period at room temperature, low temperature, and high temperature. Furthermore, the Nanoemulsion preparation exhibited higher SPF values compared to other formulations, indicating its potential effectiveness as a sunscreen for cosmetic use.

Dimensions