FORMULATION AND EVALUATION OF ORAL DISINTEGRATING TABLETS OF SALBUTAMOL SULPHATE

Authors

  • *Uma Vasi Reddy Teegala Ram Reddy College of Pharmacy Meerpet, Hyderabad, Andhra Pradesh-500 079, India.
  • Lakshmi Narasimha Reddy N Teegala Ram Reddy College of Pharmacy Meerpet, Hyderabad, Andhra Pradesh-500 079, India.
  • Poorna Chander T Teegala Ram Reddy College of Pharmacy Meerpet, Hyderabad, Andhra Pradesh-500 079, India.
  • Prashanth V Teegala Ram Reddy College of Pharmacy Meerpet, Hyderabad, Andhra Pradesh-500 079, India.

Keywords:

Mouth dissolving tablet, salbutamol sulphate, Super disintegrant, 2 adrengic agonist.

Abstract

The purpose of the present research was to compare the effect of superdisintegrants on the mouth dissolving property of salbutamol sulphate tablets. Orodispersible tablets of salbutamol sulphate of prepared using sodium starch glycollate, crosscarmellose sodium as superdisintegrants. The results revealed that the tablets containing subliming agent had a good dissolution profile. The optimized formulation showed good release profile with maximum drug being released at all time intervals. This work helped us in understanding the effect of formulation processing variables especially the super disintegrants on the drug release profile. The present study demonstrated potentials for rapid absorption improved bioavailability effective therapy and patient compliance.

Dimensions

Published

2011-03-24

Issue

Vol. 1 No. 1 (2011): 2011 Volume -1 - Issue 1

Section

Articles
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