DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMERIC METHOD FOR THE DETERMINATION OF VENLAFAXINE HYDROCHOLORIDE IN BULK AND SOLID DOSAGE FORMS

Authors

  • Sundaraganapathy R Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamil Nadu, India-637 205.
  • Jambulingam M Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamil Nadu, India-637 205.
  • Ananda Thangadurai S Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamil Nadu, India-637 205.
  • Subasini U Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamil Nadu, India-637 205.

Keywords:

Venlafaxine Hydrochloride, UV Spectrophotometer, Recovery studies.

Abstract

Determination of Venlafaxine Hydrochloride in a fixed dosage form was carried out by UV Spectrophotometric method. The absorbance values were observed for different dilutions of drug at 224nm and which are used for the estimation of drug without mutual interference of excipients. The solvent used for the dilution is Distilled water. This method obeys  Beer’s  Lambert’s  law  in  the  concentration  range  of  2-14  µg/ml.  The  results  of  analysis  have  been  validated statistically and the recovery studies confirmed the accuracy of this proposed method.

Dimensions

Published

2011-01-14

Issue

Vol. 1 No. 1 (2011): 2011 Volume -1 - Issue 1

Section

Articles
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