SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL 3,5- DISUBSTITUTED 1,2-ISOXAZOLINYL DERIVATIVES OF NAPTHALENE-1-AMINE

Authors

  • Jawahar M Smt.Sarojini Ramulamma College of Pharmacy, Mahabubnagar, AP, India - 509 001.
  • Thangamuthu S Smt.Sarojini Ramulamma College of Pharmacy, Mahabubnagar, AP, India - 509 001.
  • Arunkumar S SRM College of Pharmacy, Kattankulathur, Kanchipuram District, TN, India - 603 203.
  • Vasavi G Smt.Sarojini Ramulamma College of Pharmacy, Mahabubnagar, AP, India - 509 001.
  • Hemalatha CH Smt.Sarojini Ramulamma College of Pharmacy, Mahabubnagar, AP, India - 509 001.

Keywords:

Heterocyclic derivatives, Isoxazoline, Chalcone, Antifungal, Anticancer, MTT Assay.

Abstract

Naphthalene-1-amine known as 1-amino naphthalene is an aromatic amine possesses selective serotonin reuptake inhibitor and antimicrobiological activity. New isoxazoline derivative was synthesized from α- napthylalamine to get better biological activities like anti cancer, antibiotic, antifungal, antiviral, anti- inflammatory, antidepressant, anthelmintic. The synthesized novel heterocyclic derivative i,e isoxazoline compounds or derivatives were screened for their antimicrobial and anticancer activity and compared with standard drugs.

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Published

2012-05-28

Issue

Vol. 2 No. 2 (2012): 2012 Volume -2 - Issue 2

Section

Articles
Copyright & Licensing
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