Primary Phytochemical analysis and acute toxicity studies of Different Extracts of Celtis philippensis Blanco.

Abstract

CeltisphilippensisisalargefugacioustreethatbelongstothefamilyofUlmaceae.Itisdistributedinmost parts of India at an altitude of 1400 m and in indestructible forests. The main aim of the present study is to investigate the phytochemical analysis of leaves of Celtis philippensis and to evaluate its acute toxicity study as per OECD guidelines. The phytochemical analysis was performed by following standard procedures. The phytochemical screening results of various extracts showed the presence of alkaloids, sterols, carbohydrates, glucosides, terpenoids and saponins, tannins, gums and mucilage and flavonoids. In the acute toxicity tests, single oral administration of 5, 50, 300 & 2000 mg/kg doses of various extracts of leaves of Celtis philippensis did not show any visual symptoms of toxicity or mortality in animals during the entire 14-days observation period. Hence, it was concluded from the results that the possible oraltoxicdosesofCeltisphilippensisismorethan2000mg/kg.