A REVIEW ON FORMULATION AND EVALUATION OF POLYHERBAL ANTI –DANDRUFF HAIR SERUM

Abstract

The growths of malassezia species and on overabundance of sebum production are the main causes of dandruff, a common scalp condition marketed by flaking, itching, and irritation. The creation and testing of a polyhebral anti-dandruff hair serum using natural substances with antifungal, anti-inflammatory and conditioning qualities is the main goal of this study. In order to achieve a stable and aesthetically pleasing formulation, the serum was made with herbal extracts of neem (Azadirachta indica), marigold (Tagetes erecta), orange peel (Citrus sinensis), castor oil (Ricinus commmunis) and camphor (cinnamomum camphora), as well as appropriate excipients like triethanolamine and a gelling agent. Extraction of active phytoconstituents, concentration optimization and homogenization to attain consistent consistency were all steps in the formulation process. Numerous physicochemical criteria, such as pH, viscosity, speradability, homogeneity, appearance and stability studies under various temperature circumstances, were assessed for the produced serum. The agar well diffusion method was used to measure antifungal activity against fungi that cause dandruff. In comparison, to the control, the polyherbal serum showed notable antifungal efficacy, good stability and satisfactory physicochemical characteristics. Hair follicle feeding, fungal growth inhibition, and decreased scalp irritation were all facilitated by the herbal ingredients' synergistic activity. According to the study's findings, the polyherbal anti-dandruff hair serum is safe, efficient, and appropriate for daily use. It provides a natural substitute for synthetic anti-dandruff products with few adverse effects