A comparative study on the in-vitro performance of uncoated generic and branded Isoxsuprine Hydrochloride tablets

Abstract

The primary intension of the present work is to execute “The comparative study on the in-vitro performance of uncoated generic and branded Isoxsuprine hydrochloride tablets”. Here, we compare the 4 distinct brands of branded tablets with 1 generic tablet. The main purpose of the comparative study is to compare their stability, efficacy and other evaluation parameters with different marketed Isoxsuprine HCl tablets. Isoxsuprine hydrochloride tablets acts as beta-2 adrenergic agonist (parasympathomimetic), peripheral vasodilator, uterine relaxant (tocolytic agent). In this comparative study, we determined their efficacy and effectiveness of the tablets on the basis of various in-vitro tests like weight variation, friability, hardness, dissolution and disintegration. It can be concluded that both branded and generic isoxsuprine hydrochloride tablets meets the pharmacopoeial quality standards.