Formulation and evaluation of dispersible tablet of paracetamol and ibuprofen

Abstract

The objective of the study is to develop paracetamol and ibuprofen orally dispersible tablet using co processed

super disintegrants and comparative study with the marketed product. paracetamol and ibuprofen orally

dispersible tablet was prepared by direct compression method using co processed super disintegrants such as

cross povidone and sodium starch glycolate in different concentrations. The developed oral disintegrating

tablets were evaluated for different physical chemical evaluations like drug content, hardness, friability, weight

variation, wetting time, In vitro disintegration time, In-vitro drug release etc. All formulations had shown the

results within the prescribed limits.