Analytical Method Development And Validation Of Metronidazole In Bulk And Tablet Formulation By Uv-Spectrophotometer

Authors

  • A. Raja Reddy Associate Professor, Department of pharmaceutical analysis, CMR College of Pharmacy, Hyderabad
  • K. Likhitha Lahari M. Pharmacy Student, Department of pharmaceutical analysis, CMR College of Pharmacy, Hyderabad
  • P.Pravalika Associate Professor, Department of pharmaceutical analysis, CMR College of Pharmacy, Hyderabad
  • T. Rama Rao Principal and Professor of CMR College of Pharmacy, Medchal, Hyderabad, Telangana

Keywords:

Metronidazole, ultraviolet spectroscopy, validation, Linearity

Abstract

Metronidazole, a nitroimidazole, remains a front-line choice for treatment of infections related to inflammatory disorders of the gastrointestinal tract including colitis linked to Clostridium difficile. Metronidazole was first described in 1959 as a therapeutic agent to treat Trichomonas vaginalis infection; over time, metronidazole has been used against Giardia lamblia, Entamoeba histolytica, Clostridium difficile, Helicobacter pylori and ana- aerobic bacteria. Brand names: Acea, Anabact, Flagyl, Metrogel, Metrosa, Rosiced, Rozex, Vaginyl, Zidoval, Zyomet. Metronidazole is classified as a synthetic antibacterial and antiprotozoal agent and is administered by the intravenous route. Analysis of the UV spectra of Metronidazole enables to determine a maximum of the analytical quantification of the medicine.

Dimensions

Published

2024-04-04

Issue

Vol. 14 No. 2 (2024): 2024 Volume -14 - Issue 2

Section

Articles
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