PRELIMINARY PHYTOCHEMICAL AND DIURETIC POTENTIAL OF METHANOLIC EXTRACT OF AZIMA TETRA CAHNTHA LAM, LEAF

Abstract

Azima tetracantha.L belongs to Salvadoraceae and known as Kundali in Ayurvedic medicine. It was traditionally used for its diuretic property. Various analytical parameters such as ash value, water soluble ash, and sulphated ash done for this study. Ethyl alcoholic extract of Azima tetracantha Lam leaf were investigated diuretic activity. Its root, root bark, and leaves are administered with food as a remedy for rheumatism, stimulant, expectorant, antispasmodic and analgesic effects. Phytochemical studies reveal the presence of carbohydrates, alkaloids, flavonoids, saponins, and triterpens are also reported to be present in this plant. The diuretic activity of the extract was determined by Taylor and Topless. In this method 500mg/kg extract does not match with effect produced by the standard. But 750mg/kg body weight of the extract is almost equal to effect produced by the standard drug hydrochlorothiazide so the Azima tetracantha.L leaf extract posses the diuretic activity