Formulation and Evaluation of Poly herbal Ointment for Wound Healing activity

Abstract

Herbal therapy and herbal drugs predominates in traditional medicine as well as in alternative medicine practiced in the developed world. Among the various indications where traditional herbal medicines are used, skin and skin related disorders is ranked top. Thus, the main objective of the present study is to formulate and evaluate a poly herbal ointment with wound healing activity. Ointments were formulated using ethanolic extracts (by continuous hot Percolation-Soxhletation) of Tridax procumbens and petroleum ether extract of Cassia occidentalis were evaluated for its wound healing activity. Formulations were then tested for its physicochemical properties like loss of drying, pH, and spreadability and diffusion study and gave satisfactory results. The prepared formulations were also stable at 4ºC, 25ºC and 37ºC. Hence an attempt was made to formulate a polyherbal ointment, and to evaluate for its physical parameter, wound healing activity by excision model and to compare its activity with a marketed formulation (5% w/w betadine).Overall result of this study reveals that this is an effective polyherbal wound healing ointment.